CALL FOR PAPERS Mechanisms of Diastolic Dysfunction in Cardiovascular Disease A mouse model of heart failure with preserved ejection fraction due to chronic infusion of a low subpressor dose of angiotensin II
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چکیده
Jessica A. Regan, Adolfo Gabriele Mauro, Salvatore Carbone, Carlo Marchetti, Rabia Gill, Eleonora Mezzaroma, Juan Valle Raleigh, Fadi N. Salloum, Benjamin W. Van Tassell, Antonio Abbate, and X Stefano Toldo VCU Pauley Heart Center, Virginia Commonwealth University, Richmond, Virginia; Victoria Johnson Research Center, Virginia Commonwealth University, Richmond, Virginia; and School of Pharmacy, Virginia Commonwealth University, Richmond, Virginia
منابع مشابه
Role of the renin-angiotensin-aldosterone system in diastolic dysfunction and heart failure
Heart failure with preserved left ventricular (LV) ejection fraction is commonly viewed as the consequence of diastolic dysfunction. Hypertension is the most common cause for the development of diastolic dysfunction and LV hypertrophy leading to symptomatic hypertensive heart disease. Strict blood pressure control therefore is mandatory to prevent diastolic heart failure in patients with hypert...
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Background: Chronic hypertension causes structural and functional changes in the heart, ultimately leading to heart failure (HF), which further increases mortality and morbidit. HF is a complex clinical syndrome caused by various structural or functional abnormalities of the heart that impair the filling capacity of the ventricles. The findings of various trials have shown the association betwe...
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BACKGROUND Chronic heart failure (CHF) with preserved left ventricular (LV) ejection fraction (HFpEF) is observed in half of all patients with CHF and carries the same poor prognosis as CHF with reduced LV ejection fraction (HFrEF). In contrast to HFrEF, there is no established therapy for HFpEF. Chronic inflammation contributes to cardiac fibrosis, a crucial factor in HFpEF; however, inflammat...
متن کاملCALL FOR PAPERS Mechanisms of Diastolic Dysfunction in Cardiovascular Disease Relationship of hyperuricemia with mortality in heart failure patients with preserved ejection fraction
Takeshi Shimizu, Akiomi Yoshihisa, Yuki Kanno, Mai Takiguchi, Akihiko Sato, Shunsuke Miura, Yuichi Nakamura, Hiroyuki Yamauchi, Takashi Owada, Satoshi Abe, Takamasa Sato, Satoshi Suzuki, Masayoshi Oikawa, Takayoshi Yamaki, Koichi Sugimoto, Hiroyuki Kunii, Kazuhiko Nakazato, Hitoshi Suzuki, Shu-ichi Saitoh, and Yasuchika Takeishi Department of Cardiology and Hematology, Fukushima Medical Univers...
متن کاملChanges in the structure of the heart and blood pressure after a period of concurrent endurance-resistance training in patients with chronic heart failure
Background: Exercise improves functional capacity by improving endothelial function and musculoskeletal aerobic metabolism, but its effects on hemodynamic control are not well known. The aim of this study was to investigate the effect of aerobic and resistance trainings on structural changes and blood pressure in patients with heart failure. Materials and methods: 76 patients aged 65 to 79 year...
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تاریخ انتشار 2015